!!This displayer contains script commands. You should enable JavaScripting within your browser preferences, or use another browser!
USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
Search by
Maps
Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'USC-OGP 2-DE database' for entry
matching:
Q9BV57
USC-OGP 2-DE database
:
Q9BV57
Q9BV57
General information about the entry
View entry in simple text format
Entry name
MTND_HUMAN
Primary accession number
Q9BV57
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Submergence-induced protein-like factor; Short=Sip-L;.
Gene name
Name=ADI1
{ECO:0000255|HAMAP-Rule:MF_03154}
Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154}
ORFNames=HMFT1638
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1318
:
pI=5.55; Mw=19701
Cross-references
UniProtKB/Swiss-Prot
Q9BV57; MTND_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
MTND_HUMAN
Primary accession number
Q9BV57
Secondary accession number(s)
D6W4Y3 Q53HW3 Q53QD3 Q57YV7 Q68CK2 Q6ZSF7 Q7Z512 Q96P85 Q9NV57
Sequence was last modified on
June 1, 2001 (version 1)
Annotations were last modified on
March 15, 2017 (version 147)
Name and origin of the protein
Description
RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Submergence-induced protein-like factor; Short=Sip-L;
Gene name
Name=ADI1
{ECO:0000255|HAMAP-Rule:MF_03154}
Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154}
ORFNames=HMFT1638
Encoded on
Name=ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}; Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154}; ORFNames=HMFT1638
Keywords
3D-structure
;
Alternative splicing
;
Amino-acid biosynthesis
;
Cell membrane
;
Complete proteome
;
Cytoplasm
;
Dioxygenase
;
Direct protein sequencing
;
Iron
;
Membrane
;
Metal-binding
;
Methionine biosynthesis
;
Nucleus
;
Oxidoreductase
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AB158319; BAD10866.1
; -; mRNA
EMBL
AF087863; AAP97173.1
; -; mRNA
EMBL
AB073609; BAD38646.1
; ALT_INIT; mRNA
EMBL
AK001775; BAA91901.1
; -; mRNA
EMBL
AK127473; BAC86996.1
; -; mRNA
EMBL
AK222467; BAD96187.1
; ALT_INIT; mRNA
EMBL
AC142528; AAX82038.1
; -; Genomic_DNA
EMBL
AC114810; AAY24022.1
; -; Genomic_DNA
EMBL
CH471053; EAX01064.1
; -; Genomic_DNA
EMBL
CH471053; EAX01065.1
; -; Genomic_DNA
EMBL
BC001467; AAH01467.1
; -; mRNA
EMBL
AF403478; AAL25800.1
; ALT_INIT; mRNA
CCDS
CCDS1653.1; -. [Q9BV57-1]
; .
CCDS
CCDS77380.1; -. [Q9BV57-2]
; .
RefSeq
NP_001293006.1; NM_001306077.1. [Q9BV57-2]
; .
RefSeq
NP_060739.2; NM_018269.3. [Q9BV57-1]
; .
UniGene
Hs.502773; -
; .
PDB
4QGN; X-ray
; 3.05 A; A=1-179
PDBsum
4QGN; -
; .
ProteinModelPortal
Q9BV57; -
; .
SMR
Q9BV57; -
; .
BioGrid
120547; 17
; .
IntAct
Q9BV57; 3
; .
STRING
9606.ENSP00000333666; -
; .
DrugBank
DB02325; Isopropyl Alcohol
; .
iPTMnet
Q9BV57; -
; .
PhosphoSitePlus
Q9BV57; -
; .
BioMuta
ADI1; -
; .
DMDM
74733289; -
; .
EPD
Q9BV57; -
; .
MaxQB
Q9BV57; -
; .
PaxDb
Q9BV57; -
; .
PeptideAtlas
Q9BV57; -
; .
PRIDE
Q9BV57; -
; .
TopDownProteomics
Q9BV57-1; -. [Q9BV57-1]
; .
TopDownProteomics
Q9BV57-2; -. [Q9BV57-2]
; .
DNASU
55256; -
; .
Ensembl
ENST00000327435; ENSP00000333666
; ENSG00000182551. [Q9BV57-1]; .
Ensembl
ENST00000382093; ENSP00000371525
; ENSG00000182551. [Q9BV57-2]; .
GeneID
55256; -
; .
KEGG
hsa:55256; -
; .
UCSC
uc002qxp.5; human. [Q9BV57-1]
; .
CTD
55256; -
; .
DisGeNET
55256; -
; .
GeneCards
ADI1; -
; .
HGNC
HGNC:30576; ADI1
; .
HPA
HPA035403; -
; .
HPA
HPA035404; -
; .
MIM
613400; gene
; .
neXtProt
NX_Q9BV57; -
; .
OpenTargets
ENSG00000182551; -
; .
PharmGKB
PA143485291; -
; .
eggNOG
KOG2107; Eukaryota
; .
eggNOG
COG1791; LUCA
; .
GeneTree
ENSGT00390000008195; -
; .
HOVERGEN
HBG081992; -
; .
InParanoid
Q9BV57; -
; .
KO
K08967; -
; .
OMA
QWIRIEV; -
; .
OrthoDB
EOG091G0OM4; -
; .
PhylomeDB
Q9BV57; -
; .
TreeFam
TF300231; -
; .
Reactome
R-HSA-1237112; Methionine salvage pathway
; .
UniPathway
UPA00904; UER00878
; .
ChiTaRS
ADI1; human
; .
GeneWiki
ADI1; -
; .
GenomeRNAi
55256; -
; .
PRO
PR:Q9BV57; -
; .
Proteomes
UP000005640; Chromosome 2
; .
Bgee
ENSG00000182551; -
; .
CleanEx
HS_ADI1; -
; .
ExpressionAtlas
Q9BV57; baseline and differential
; .
Genevisible
Q9BV57; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0005886; C:plasma membrane
; IDA:UniProtKB; .
GO
GO:0010309; F:acireductone dioxygenase [iron(II)-requiring] activity
; TAS:Reactome; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0016491; F:oxidoreductase activity
; IDA:UniProtKB; .
GO
GO:0019509; P:L-methionine salvage from methylthioadenosine
; IDA:UniProtKB; .
Gene3D
2.60.120.10; -
; 1; .
HAMAP
MF_03154; Salvage_MtnD_euk
; 1; .
InterPro
IPR004313; ARD
; .
InterPro
IPR027496; ARD_euk
; .
InterPro
IPR014710; RmlC-like_jellyroll
; .
InterPro
IPR011051; RmlC_Cupin
; .
PANTHER
PTHR23418; PTHR23418
; 1; .
Pfam
PF03079; ARD
; 1; .
SUPFAM
SSF51182; SSF51182
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
[
Home
]